Thom LaBean
Professor
- thlabean@ncsu.edu
- Engineering Building I 3030D
- Visit My Website
LaBean earned his BS in biochemistry from the Honors College at Michigan State University, and his PhD in biochemistry from the University of Pennsylvania. He studied protein design as a postdoctoral fellow at Duke University. He then ran his own group as research professor with appointments in the departments of Computer Science, Chemistry, and Biomedical Engineering at Duke. LaBean joined MSE@NCSU in 2011. Throughout his career, LaBean has studied the structure, evolution, and engineering of biopolymers (biomacromolecules and materials assembled from them). Current research projects involve the design, construction, and testing of self-assembling DNA nanostructures for applications in nanomedicine, molecular materials, and biomimetic fabrication of nanoelectronics.
Publications
- A Functional RNA-Origami as Direct Thrombin Inhibitor with Fast-acting and Specific Single-Molecule Reversal Agents in vivo model (2024)
- Utilizing multiscale engineered biomaterials to examine
TGF‐β ‐mediated myofibroblastic differentiation (2024) - DNA aerogels and DNA-wrapped CNT aerogels for neuromorphic applications (2022)
- Modeling and characterization of stochastic resistive switching in single Ag2S nanowires (2022)
- Resistive switching of two-dimensional Ag2S nanowire networks for neuromorphic applications (2022)
- Mechanical and Electrical Properties of DNA Hydrogel-Based Composites Containing Self-Assembled Three-Dimensional Nanocircuits (2021)
- Multivalent Aptamer‐Functionalized Single‐Strand RNA Origami as Effective, Target‐Specific Anticoagulants with Corresponding Reversal Agents (2021)
- Self-Assembling Nucleic Acid Nanostructures Functionalized with Aptamers (2021)
- Genetically Encoded, Functional Single-Strand RNA Origami: Anticoagulant (2019)
- Engineered Diblock Polypeptides Improve DNA and Gold Solubility during Molecular Assembly (2017)